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IRaPPA: information retrieval based integration of biophysical models for protein assembly selection

MOTIVATION: In order to function, proteins frequently bind to one another and form 3D assemblies. Knowledge of the atomic details of these structures helps our understanding of how proteins work together, how mutations can lead to disease, and facilitates the designing of drugs which prevent or mimi...

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Detalles Bibliográficos
Autores principales: Moal, Iain H, Barradas-Bautista, Didier, Jiménez-García, Brian, Torchala, Mieczyslaw, van der Velde, Arjan, Vreven, Thom, Weng, Zhiping, Bates, Paul A, Fernández-Recio, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783285/
https://www.ncbi.nlm.nih.gov/pubmed/28200016
http://dx.doi.org/10.1093/bioinformatics/btx068