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IRaPPA: information retrieval based integration of biophysical models for protein assembly selection
MOTIVATION: In order to function, proteins frequently bind to one another and form 3D assemblies. Knowledge of the atomic details of these structures helps our understanding of how proteins work together, how mutations can lead to disease, and facilitates the designing of drugs which prevent or mimi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783285/ https://www.ncbi.nlm.nih.gov/pubmed/28200016 http://dx.doi.org/10.1093/bioinformatics/btx068 |