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Development of an activity-based probe for acyl-protein thioesterases

Protein palmitoylation is a dynamic post-translational modification (PTM) important for cellular functions such as protein stability, trafficking, localization, and protein-protein interactions. S-palmitoylation occurs via the addition of palmitate to cysteine residues via a thioester linkage, catal...

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Detalles Bibliográficos
Autores principales: Garland, Megan, Schulze, Christopher J., Foe, Ian T., van der Linden, Wouter A., Child, Matthew A., Bogyo, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783350/
https://www.ncbi.nlm.nih.gov/pubmed/29364904
http://dx.doi.org/10.1371/journal.pone.0190255