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Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease
INTRODUCTION: Overt fibrostenotic disease is a relative contraindication for anti-TNF therapy in Crohn’s disease. We hypothesized that subclinical fibrosis may also contribute to an incomplete response to anti-TNF therapy before the onset of symptomatic stenosis. METHODS: In a previous trial, patien...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783363/ https://www.ncbi.nlm.nih.gov/pubmed/29364909 http://dx.doi.org/10.1371/journal.pone.0190999 |