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Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease

INTRODUCTION: Overt fibrostenotic disease is a relative contraindication for anti-TNF therapy in Crohn’s disease. We hypothesized that subclinical fibrosis may also contribute to an incomplete response to anti-TNF therapy before the onset of symptomatic stenosis. METHODS: In a previous trial, patien...

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Detalles Bibliográficos
Autores principales:	de Bruyn, Jessica R., Becker, Marte A., Steenkamer, Jessica, Wildenberg, Manon E., Meijer, Sybren L., Buskens, Christianne J., Bemelman, Willem A., Löwenberg, Mark, Ponsioen, Cyriel Y., van den Brink, Gijs R., D’Haens, Geert R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783363/ https://www.ncbi.nlm.nih.gov/pubmed/29364909 http://dx.doi.org/10.1371/journal.pone.0190999

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