Detection of DNA oligonucleotides with base mutations by terahertz spectroscopy and microstructures

DNA oligonucleotides with a 5-base mutation at the 3'-terminus were investigated by terahertz (THz) spectroscopy in a marker-free manner. The four single-stranded oligonucleotides with 17nt have been detected with specificity on a microfluidic chip, and corroborated by spectral measurements wit...

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Detalles Bibliográficos
Autores principales: Tang, Mingjie, Zhang, Mingkun, Yan, Shihan, Xia, Liangping, Yang, Zhongbo, Du, Chunlei, Cui, Hong-Liang, Wei, Dongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783420/
https://www.ncbi.nlm.nih.gov/pubmed/29364930
http://dx.doi.org/10.1371/journal.pone.0191515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783420/
https://www.ncbi.nlm.nih.gov/pubmed/29364930
http://dx.doi.org/10.1371/journal.pone.0191515

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