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Downregulation of miR-29b targets DNMT3b to suppress cellular apoptosis and enhance proliferation in pancreatic cancer

As one of the most aggressive types of tumor, pancreatic cancer is a principal cause of tumor-associated mortality. Negative associations between microRNA-29 (miR-29) and DNA methyltransferases (DNMT) 3a and 3b have been demonstrated to be associated with the carcinogenesis of a number of types of c...

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Detalles Bibliográficos
Autores principales: Wang, Li-Hua, Huang, Ju, Wu, Cheng-Rong, Huang, Liu-Ye, Cui, Jun, Xing, Zhi-Zhi, Zhao, Chun-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783451/
https://www.ncbi.nlm.nih.gov/pubmed/29207141
http://dx.doi.org/10.3892/mmr.2017.8145