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P2X7 receptor antagonist protects retinal ganglion cells by inhibiting microglial activation in a rat chronic ocular hypertension model

Microglial activation and the release of pro-inflammatory cytokines occur during early glaucoma. However, the exact mechanism underlying the initiation of the microglial activation process remains unclear. Thus, the present study investigated the potential role of a purine receptor subtype, the P2X...

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Detalles Bibliográficos
Autores principales: Dong, Lingdan, Hu, Yanhong, Zhou, Long, Cheng, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783460/
https://www.ncbi.nlm.nih.gov/pubmed/29207073
http://dx.doi.org/10.3892/mmr.2017.8137