Cargando…

P2X7 receptor antagonist protects retinal ganglion cells by inhibiting microglial activation in a rat chronic ocular hypertension model

Microglial activation and the release of pro-inflammatory cytokines occur during early glaucoma. However, the exact mechanism underlying the initiation of the microglial activation process remains unclear. Thus, the present study investigated the potential role of a purine receptor subtype, the P2X...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, Lingdan, Hu, Yanhong, Zhou, Long, Cheng, Xianglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783460/ https://www.ncbi.nlm.nih.gov/pubmed/29207073 http://dx.doi.org/10.3892/mmr.2017.8137

Ejemplares similares

Calcium channels are involved in EphB/ephrinB reverse signaling-induced apoptosis in a rat chronic ocular hypertension model
por: Dong, Lingdan, et al.
Publicado: (2018)

MicroRNA-93/STAT3 signalling pathway mediates retinal microglial activation and protects retinal ganglion cells in an acute ocular hypertension model
por: Wang, Yayi, et al.
Publicado: (2021)

Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury
por: Fu, Lin, et al.
Publicado: (2018)

Caveolin-1 Protects Retinal Ganglion Cells against Acute Ocular Hypertension Injury via Modulating Microglial Phenotypes and Distribution and Activating AKT pathway
por: Zhang, Liwei, et al.
Publicado: (2017)

Protection of the Retinal Ganglion Cells: Intravitreal Injection of Resveratrol in Mouse Model of Ocular Hypertension
por: Cao, Kejia, et al.
Publicado: (2020)

Mouse model of ocular hypertension with retinal ganglion cell degeneration
por: Mukai, Ryo, et al.
Publicado: (2019)

Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension
por: Rocha, Lorena Raquel, et al.
Publicado: (2019)

ATP-P2X(7)R-mediated microglia senescence aggravates retinal ganglion cell injury in chronic ocular hypertension
por: Wei, Miao, et al.
Publicado: (2023)

Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model
por: Chiu, Kin, et al.
Publicado: (2009)

Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model
por: Chiu, Kin, et al.
Publicado: (2009)

Retinal Ganglion Cell Degeneration in a Rat Magnetic Bead Model of Ocular Hypertensive Glaucoma
por: Tribble, James R., et al.
Publicado: (2021)

Protection of Retinal Ganglion Cells and Retinal Vasculature by Lycium Barbarum Polysaccharides in a Mouse Model of Acute Ocular Hypertension
por: Mi, Xue-Song, et al.
Publicado: (2012)

JUN is important for ocular hypertension-induced retinal ganglion cell degeneration
por: Syc-Mazurek, Stephanie B, et al.
Publicado: (2017)

Activation of adenosine A(3) receptor protects retinal ganglion cells from degeneration induced by ocular hypertension
por: Boia, Raquel, et al.
Publicado: (2020)

Neuronal p58(IPK) Protects Retinal Ganglion Cells Independently of Macrophage/Microglia Activation in Ocular Hypertension
por: McLaughlin, Todd, et al.
Publicado: (2023)

Alpha B-crystallin improved survival of retinal ganglion cells in a rat model of acute ocular hypertension☆
por: Wu, Zhihong, et al.
Publicado: (2012)

Selective vulnerability of the intermediate retinal capillary plexus precedes retinal ganglion cell loss in ocular hypertension
por: Pitale, Priyamvada M., et al.
Publicado: (2022)

Protective effect of a JNK inhibitor against retinal ganglion cell loss induced by acute moderate ocular hypertension
por: Sun, Hui, et al.
Publicado: (2011)

Long-Term Protection of Retinal Ganglion Cells and Visual Function by Brain-Derived Neurotrophic Factor in Mice With Ocular Hypertension
por: Feng, Liang, et al.
Publicado: (2016)

Protective effects of blocking PD-1 pathway on retinal ganglion cells in a mouse model of chronic ocular hypertension
por: Sheng, Siqi, et al.
Publicado: (2023)

Ocular Hypertension Drives Remodeling of AMPA Receptors in Select Populations of Retinal Ganglion Cells
por: Sladek, Asia L., et al.
Publicado: (2020)

Retinal microglial activation in glaucoma: evolution over time in a unilateral ocular hypertension model
por: Fernández-Albarral, José A., et al.
Publicado: (2021)

Microglial dynamics after axotomy-induced retinal ganglion cell death
por: Nadal-Nicolás, Francisco M., et al.
Publicado: (2017)

Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus
por: Bhandari, Ashish, et al.
Publicado: (2019)

Keratin8 Deficiency Aggravates Retinal Ganglion Cell Damage Under Acute Ocular Hypertension
por: Zhang, Chengshou, et al.
Publicado: (2023)

Characterization of the role of autophagy in retinal ganglion cell survival over time using a rat model of chronic ocular hypertension
por: Lee, Si Hyung, et al.
Publicado: (2021)

Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line
por: Hong, Samin, et al.
Publicado: (2007)

Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma
por: Nam, Mi-Hyun, et al.
Publicado: (2022)

Effects of β-adrenergic receptor antagonists on oxidative stress in purified rat retinal ganglion cells
por: Yu, Zi-Kui, et al.
Publicado: (2007)

Ocular direct current stimulation affects retinal ganglion cells
por: Blum, Maren-Christina, et al.
Publicado: (2021)

Protective effect of leukemia inhibitory factor on the retinal injury induced by acute ocular hypertension in rats
por: Lv, Jiexuan, et al.
Publicado: (2022)

P2X7 receptor antagonist improves gastrointestinal disorders in spontaneously hypertensive rats
por: de Oliveira, K.B.V., et al.
Publicado: (2023)

Retraction Note: Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line
por: Hong, Samin, et al.
Publicado: (2023)

Neuroprotective effect of the calcium channel blocker nilvadipine on retinal ganglion cell death in a mouse ocular hypertension model
por: Tsuruga, Hidekazu, et al.
Publicado: (2023)

Heat shock protein 72 confers protection in retinal ganglion cells and lateral geniculate nucleus neurons via blockade of the SAPK/JNK pathway in a chronic ocular-hypertensive rat model
por: Li, Ning, et al.
Publicado: (2014)

Effects of a Metabotropic Glutamate 1 Receptor Antagonist on Light Responses of Retinal Ganglion Cells in a Rat Model of Retinitis Pigmentosa
por: Jensen, Ralph J.
Publicado: (2013)

Role of Oxidative Stress in Ocular Diseases Associated with Retinal Ganglion Cells Degeneration
por: Kang, Eugene Yu-Chuan, et al.
Publicado: (2021)

The Nrf2 Signaling in Retinal Ganglion Cells under Oxidative Stress in Ocular Neurodegenerative Diseases
por: Liu, Xiu-Fen, et al.
Publicado: (2018)

Panton–Valentine Leukocidin Colocalizes with Retinal Ganglion and Amacrine Cells and Activates Glial Reactions and Microglial Apoptosis
por: Liu, XuanLi, et al.
Publicado: (2018)

Frequency Responses of Rat Retinal Ganglion Cells
por: Hadjinicolaou, Alex E., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_so07vuoutqb15fq0mduovtkshp