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UNC0638, a G9a inhibitor, suppresses epithelial-mesenchymal transition-mediated cellular migration and invasion in triple negative breast cancer

Triple-negative breast cancer (TNBC) is associated with an aggressive clinical history, high risk of recurrence and metastasis, and shorter patient survival due to lack of targeted therapy. In the present study, UNC0638, a chemical G9a inhibitor, was identified to suppress TNBC cell invasion and mig...

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Detalles Bibliográficos
Autores principales: Liu, Xiang-Rong, Zhou, Li-Hua, Hu, Jian-Xin, Liu, Li-Min, Wan, Hui-Ping, Zhang, Xi-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783465/
https://www.ncbi.nlm.nih.gov/pubmed/29207160
http://dx.doi.org/10.3892/mmr.2017.8190