Cargando…

UNC0638, a G9a inhibitor, suppresses epithelial-mesenchymal transition-mediated cellular migration and invasion in triple negative breast cancer

Triple-negative breast cancer (TNBC) is associated with an aggressive clinical history, high risk of recurrence and metastasis, and shorter patient survival due to lack of targeted therapy. In the present study, UNC0638, a chemical G9a inhibitor, was identified to suppress TNBC cell invasion and mig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiang-Rong, Zhou, Li-Hua, Hu, Jian-Xin, Liu, Li-Min, Wan, Hui-Ping, Zhang, Xi-Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783465/ https://www.ncbi.nlm.nih.gov/pubmed/29207160 http://dx.doi.org/10.3892/mmr.2017.8190

Ejemplares similares

Silencing of Prrx1b suppresses cellular proliferation, migration, invasion and epithelial–mesenchymal transition in triple‐negative breast cancer
por: Lv, Zhi‐Dong, et al.
Publicado: (2016)

Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells
por: Zhang, Panshi, et al.
Publicado: (2016)

miR‐655 suppresses epithelial‐to‐mesenchymal transition by targeting Prrx1 in triple‐negative breast cancer
por: Lv, Zhi‐Dong, et al.
Publicado: (2016)

Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells
por: Zhang, Yingzi, et al.
Publicado: (2021)

Knockdown of Collagen Triple Helix Repeat Containing 1 (CTHRC1) Inhibits Epithelial–Mesenchymal Transition and Cellular Migration in Glioblastoma Cells
por: Liu, Jianpeng, et al.
Publicado: (2017)

LINC0638 lncRNA is involved in the local recurrence of melanoma following surgical resection
por: Xiao, Weirong, et al.
Publicado: (2019)

NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling
por: Zhang, Jianchao, et al.
Publicado: (2016)

Curcumol enhances the anti-tumor effects of metformin via suppressing epithelial-mesenchymal transition in triple-negative breast cancer
por: Wang, Gangyue, et al.
Publicado: (2020)

Inhibition of ERRα suppresses epithelial mesenchymal transition of triple negative breast cancer cells by directly targeting fibronectin
por: Wu, Ying-Min, et al.
Publicado: (2015)

PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer
por: Al-Khadairi, Ghaneya, et al.
Publicado: (2019)

Huaier polysaccharides suppress triple-negative breast cancer metastasis and epithelial-mesenchymal transition by inducing autophagic degradation of Snail
por: Tian, Yuan, et al.
Publicado: (2021)

The Response of Triple-Negative Breast Cancer to Neoadjuvant Chemotherapy and the Epithelial–Mesenchymal Transition
por: Zapperi, Stefano, et al.
Publicado: (2023)

Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathway
por: Bao, Chang, et al.
Publicado: (2021)

Intercellular Communication Reveals Therapeutic Potential of Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer
por: Liu, Yang, et al.
Publicado: (2022)

Dihydrotanshinone-I modulates Epithelial Mesenchymal Transition (EMT) Thereby Impairing Migration and Clonogenicity of Triple Negative Breast Cancer Cells
por: Kashyap, Akanksha, et al.
Publicado: (2021)

Effects of miR-93 on epithelial-to-mesenchymal transition and vasculogenic mimicry in triple-negative breast cancer cells
por: An, Gaili, et al.
Publicado: (2021)

Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer
por: Bhatt, Akshita B., et al.
Publicado: (2019)

Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple‐negative breast cancer
por: Yamamoto, Mizuki, et al.
Publicado: (2017)

Classification of triple negative breast cancer by epithelial mesenchymal transition and the tumor immune microenvironment
por: Font-Clos, Francesc, et al.
Publicado: (2022)

Abstract No. : ABS0638: Comparison of transforaminal epidural injection vs trigger point injection for low back pain.
por: Bathia, Ravi
Publicado: (2022)

miR-100 Induces Epithelial-Mesenchymal Transition but Suppresses Tumorigenesis, Migration and Invasion
por: Chen, Dahu, et al.
Publicado: (2014)

A Six-Epithelial–Mesenchymal Transition Gene Signature May Predict Metastasis of Triple-Negative Breast Cancer
por: Wei, Li Yuan, et al.
Publicado: (2020)

RRP12 suppresses cell migration and invasion in colorectal cancer cell via regulation of epithelial-mesenchymal transition
por: An, Gaili, et al.
Publicado: (2023)

Ventilagolin Suppresses Migration, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells by Downregulating Pim-1
por: Liu, Ying, et al.
Publicado: (2021)

ESR2 Drives Mesenchymal-to-Epithelial Transition in Triple-Negative Breast Cancer and Tumorigenesis In Vivo
por: Piperigkou, Zoi, et al.
Publicado: (2022)

MeCP2 inhibits proliferation and migration of breast cancer via suppression of epithelial‐mesenchymal transition
por: Jiang, Wei, et al.
Publicado: (2020)

High expression of CD47 in triple negative breast cancer is associated with epithelial-mesenchymal transition and poor prognosis
por: Yuan, Jingping, et al.
Publicado: (2019)

Down‐regulation of PDGFRβ suppresses invasion and migration in osteosarcoma cells by influencing epithelial–mesenchymal transition
por: Xing, Sining, et al.
Publicado: (2020)

Chemotherapeutic Stress Influences Epithelial–Mesenchymal Transition and Stemness in Cancer Stem Cells of Triple-Negative Breast Cancer
por: Li, Xiao, et al.
Publicado: (2020)

Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells
por: Wang, Qian, et al.
Publicado: (2017)

FRK inhibits breast cancer cell migration and invasion by suppressing epithelial-mesenchymal transition
por: Ogunbolude, Yetunde, et al.
Publicado: (2017)

Ginsenoside Rg3 Inhibits Migration and Invasion of Nasopharyngeal Carcinoma Cells and Suppresses Epithelial Mesenchymal Transition
por: Wang, Dingkun, et al.
Publicado: (2019)

Escin Ia suppresses the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression
por: Wang, Yuhui, et al.
Publicado: (2016)

Identification of microRNA clusters cooperatively acting on epithelial to mesenchymal transition in triple negative breast cancer
por: Cantini, Laura, et al.
Publicado: (2019)

Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition
por: Garcia, Elizabeth, et al.
Publicado: (2021)

Annurca apple polyphenol extract promotes mesenchymal-to-epithelial transition and inhibits migration in triple-negative breast cancer cells through ROS/JNK signaling
por: Vuoso, Daniela Cristina, et al.
Publicado: (2020)

Nrf3 promotes the proliferation and migration of triple‑negative breast cancer by activating PI3K/AKT/mTOR and epithelial‑mesenchymal transition
por: Chen, Wan-Meng, et al.
Publicado: (2023)

Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway
por: Jo, Su Ji, et al.
Publicado: (2017)

Knockdown of Thymidine Kinase 1 Suppresses Cell Proliferation, Invasion, Migration, and Epithelial–Mesenchymal Transition in Thyroid Carcinoma Cells
por: Liu, Chang, et al.
Publicado: (2020)

GDF10 inhibits proliferation and epithelial-mesenchymal transition in triple‐negative breast cancer via upregulation of Smad7
por: Zhou, Tian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kbgtdje6ee20hj9536gjeu9tob