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High glucose/lysophosphatidylcholine levels stimulate extracellular matrix deposition in diabetic nephropathy via platelet-activating factor receptor

Platelet-activating factor (PAF), protein kinase C (PKC)βI, transforming growth factor (TGF)-β1 and aberrant extracellular matrix (ECM) deposition have been associated with diabetic nephropathy (DN). However, the mechanistic basis underlying this association remains to be elucidated. The present stu...

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Detalles Bibliográficos
Autores principales: Zhou, Su-Xian, Huo, Dong-Mei, He, Xiao-Yun, Yu, Ping, Xiao, Yan-Hua, Ou, Chun-Lin, Jiang, Ren-Mei, Li, Dan, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783481/
https://www.ncbi.nlm.nih.gov/pubmed/29207067
http://dx.doi.org/10.3892/mmr.2017.8102