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Histone deacetylase 2 is involved in µ-opioid receptor suppression in the spinal dorsal horn in a rat model of chronic pancreatitis pain

Chronic pain occurs in ~85–90% of chronic pancreatitis (CP) patients. However, as the pathogenesis of CP pain remains to be fully understood, the current therapies for CP pain remain inadequate. Emerging evidence has suggested that the epigenetic modulations of genes are involved in chronic pain. In...

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Detalles Bibliográficos
Autores principales: Liao, Yong-Hui, Wang, Jian, Wei, Yan-Yan, Zhang, Ting, Zhang, Yong, Zuo, Zhong-Fu, Teng, Xiao-Yu, Li, Yun-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783494/
https://www.ncbi.nlm.nih.gov/pubmed/29257262
http://dx.doi.org/10.3892/mmr.2017.8245