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CRISPR/Cas9 targeting of the androgen receptor suppresses the growth of LNCaP human prostate cancer cells

Androgens have been recognized to be primary causative agents of prostate cancer. Following binding to the androgen receptor (AR), androgens serve important roles in the carcinogenesis of prostate cancers. ARs serve an important role during all stages of prostate cancer, and inhibiting their functio...

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Detalles Bibliográficos
Autores principales: Wei, Chaogang, Wang, Fengjiao, Liu, Wei, Zhao, Wenlu, Yang, Yi, Li, Kai, Xiao, Li, Shen, Junkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783506/
https://www.ncbi.nlm.nih.gov/pubmed/29257308
http://dx.doi.org/10.3892/mmr.2017.8257