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Less hippocampal neuronal death in young gerbils following transient global cerebral ischemia is associated with long-term maintenance of insulin-like growth factor 1 and its receptors in the hippocampal CA1 region

Insulin-like growth factor 1 (IGF-1) is a well-known growth factor with well-defined neuroprotective effects against cerebral ischemia. However, the age-dependent differences in the expression of IGF-1 and its receptor (IGF-1R) in the brain following transient cerebral ischemia (TCI) have not been e...

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Detalles Bibliográficos
Autores principales: Yan, Bing Chun, Wang, Jie, Cao, Jianwen, Won, Moo-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783526/
https://www.ncbi.nlm.nih.gov/pubmed/29257289
http://dx.doi.org/10.3892/mmr.2017.8243