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Neat1 regulates oxidized low-density lipoprotein-induced inflammation and lipid uptake in macrophages via paraspeckle formation

Oxidized low-density lipoprotein (oxLDL) induces macrophage inflammation and lipid uptake, and serves important roles in the development of atherosclerosis. The long non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (neat1) has two isoforms; the longer isoform, neat1_2, mediates the...

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Detalles Bibliográficos
Autores principales: Huang-Fu, Ning, Cheng, Jing-Song, Wang, Yong, Li, Zhen-Wei, Wang, Sheng-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783531/
https://www.ncbi.nlm.nih.gov/pubmed/29257236
http://dx.doi.org/10.3892/mmr.2017.8211