Cargando…

Neat1 regulates oxidized low-density lipoprotein-induced inflammation and lipid uptake in macrophages via paraspeckle formation

Oxidized low-density lipoprotein (oxLDL) induces macrophage inflammation and lipid uptake, and serves important roles in the development of atherosclerosis. The long non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (neat1) has two isoforms; the longer isoform, neat1_2, mediates the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang-Fu, Ning, Cheng, Jing-Song, Wang, Yong, Li, Zhen-Wei, Wang, Sheng-Huang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783531/ https://www.ncbi.nlm.nih.gov/pubmed/29257236 http://dx.doi.org/10.3892/mmr.2017.8211

Ejemplares similares

NEAT1 and Paraspeckles in Cancer Development and Chemoresistance
por: Pisani, Gabriel, et al.
Publicado: (2020)

A toolkit for the identification of NEAT1_2/paraspeckle modulators
por: An, Haiyan, et al.
Publicado: (2022)

NEAT1 and paraspeckles in neurodegenerative diseases: A missing lnc found?
por: An, Haiyan, et al.
Publicado: (2018)

Species-specific formation of paraspeckles in intestinal epithelium revealed by characterization of NEAT1 in naked mole-rat
por: Yamada, Akihiro, et al.
Publicado: (2022)

Metformin protects against oxidized low density lipoprotein-induced macrophage apoptosis and inhibits lipid uptake
por: Huangfu, Ning, et al.
Publicado: (2018)

Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1
por: Barra, Jasmine, et al.
Publicado: (2020)

Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia
por: Godet, Anne-Claire, et al.
Publicado: (2022)

Functional dissection of NEAT1 using genome editing reveals substantial localization of the NEAT1_1 isoform outside paraspeckles
por: Li, Ruohan, et al.
Publicado: (2017)

Forced isoform switching of Neat1_1 to Neat1_2 leads to the loss of Neat1_1 and the hyperformation of paraspeckles but does not affect the development and growth of mice
por: Isobe, Momo, et al.
Publicado: (2020)

NEAT1 Long Noncoding RNA and Paraspeckle Bodies Modulate HIV-1 Posttranscriptional Expression
por: Zhang, Quan, et al.
Publicado: (2013)

Phosphorothioate oligonucleotides can displace NEAT1 RNA and form nuclear paraspeckle-like structures
por: Shen, Wen, et al.
Publicado: (2014)

Matrix stiffness-sensitive long noncoding RNA NEAT1 seeded paraspeckles in cancer cells
por: Todorovski, Vanja, et al.
Publicado: (2020)

Oxidized high-density lipoprotein promotes CD36 palmitoylation and increases lipid uptake in macrophages
por: Zhang, Yun, et al.
Publicado: (2022)

Native low density lipoprotein promotes lipid raft formation in macrophages
por: SONG, JIAN, et al.
Publicado: (2016)

LncRNA NEAT1 in Paraspeckles: A Structural Scaffold for Cellular DNA Damage Response Systems?
por: Taiana, Elisa, et al.
Publicado: (2020)

The c-Myc-regulated lncRNA NEAT1 and paraspeckles modulate imatinib-induced apoptosis in CML cells
por: Zeng, Chengwu, et al.
Publicado: (2018)

Highly Ordered Spatial Organization of the Structural Long Noncoding NEAT1 RNAs within Paraspeckle Nuclear Bodies
por: Souquere, Sylvie, et al.
Publicado: (2010)

The Hepatitis Delta Virus accumulation requires paraspeckle components and affects NEAT1 level and PSP1 localization
por: Beeharry, Yasnee, et al.
Publicado: (2018)

mTOR regulates aerobic glycolysis through NEAT1 and nuclear paraspeckle-mediated mechanism in hepatocellular carcinoma
por: Zhang, Hong, et al.
Publicado: (2022)

Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival
por: Choudhry, H, et al.
Publicado: (2015)

The mechanosensitive lncRNA Neat1 promotes osteoblast function through paraspeckle-dependent Smurf1 mRNA retention
por: Liu, Caizhi, et al.
Publicado: (2022)

Structural analyses of NEAT1 lncRNAs suggest long-range RNA interactions that may contribute to paraspeckle architecture
por: Lin, Yizhu, et al.
Publicado: (2018)

Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA
por: Anantharaman, Aparna, et al.
Publicado: (2016)

Erratum: Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival
por: Choudhry, H, et al.
Publicado: (2015)

Compromised paraspeckle formation as a pathogenic factor in FUSopathies
por: Shelkovnikova, Tatyana A., et al.
Publicado: (2014)

Polyphenolics from Syzygium brachythyrsum Inhibits Oxidized Low-Density Lipoprotein-Induced Macrophage-Derived Foam Cell Formation and Inflammation
por: Chen, Xue-Lian, et al.
Publicado: (2022)

Long Non-Coding RNA Nuclear Paraspeckle Assembly Transcript 1 (NEAT1)Relieves Sepsis-Induced Kidney Injury and Lipopolysaccharide (LPS)-Induced Inflammation in HK-2 Cells
por: Gao, Cheng, et al.
Publicado: (2020)

C9-ALS/FTD-linked proline–arginine dipeptide repeat protein associates with paraspeckle components and increases paraspeckle formation
por: Suzuki, Hiroaki, et al.
Publicado: (2019)

USP10 deletion inhibits macrophage-derived foam cell formation and cellular-oxidized low density lipoprotein uptake by promoting the degradation of CD36
por: Xia, Xiaohong, et al.
Publicado: (2020)

The role of long non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (NEAT1) in chronic periodontitis progression
por: Zhang, Lei, et al.
Publicado: (2022)

Macrophage Differentiation from Monocytes Is Influenced by the Lipid Oxidation Degree of Low Density Lipoprotein
por: Seo, Jin-Won, et al.
Publicado: (2015)

Isoborneol Attenuates Low-Density Lipoprotein Accumulation and Foam Cell Formation in Macrophages
por: Wang, Yunfei, et al.
Publicado: (2020)

How to build a paraspeckle
por: Sasaki, Yasnory TF, et al.
Publicado: (2009)

Paraspeckles: Paragons of functional aggregation
por: Courchaine, Edward, et al.
Publicado: (2015)

TDP43 Exacerbates Atherosclerosis Progression by Promoting Inflammation and Lipid Uptake of Macrophages
por: Huangfu, Ning, et al.
Publicado: (2021)

Whole-Cell Analysis of Low-Density Lipoprotein Uptake by Macrophages Using STEM Tomography
por: Baudoin, Jean-Pierre, et al.
Publicado: (2013)

CD9 Tetraspanin Interacts with CD36 on the Surface of Macrophages: A Possible Regulatory Influence on Uptake of Oxidized Low Density Lipoprotein
por: Huang, Wenxin, et al.
Publicado: (2011)

Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation
por: Grosch, Markus, et al.
Publicado: (2020)

Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low‐Density Lipoproteins and Increasing Their Uptake by Macrophages
por: Demina, Ekaterina P., et al.
Publicado: (2021)

Paraspeckles may provide stress relief
por: Leslie, Mitch
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_9k1oqgelskhj3bjv827gv10ov0