Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease

BRAF V600E mutations occur frequently in malignant melanoma, but are rare in most malignant glioma subtypes. Besides, more benign brain tumors such as ganglioglioma, dysembryoblastic neuroepithelial tumours and supratentorial pilocytic astrocytomas, only pleomorphic xanthoastrocytomas (50–78%) and e...

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Detalles Bibliográficos
Autores principales: Burger, Michael C., Ronellenfitsch, Michael W., Lorenz, Nadja I., Wagner, Marlies, Voss, Martin, Capper, David, Tzaridis, Theophilos, Herrlinger, Ulrich, Steinbach, Joachim P., Stoffels, Gabriele, Langen, Karl-Josef, Brandts, Christian, Senft, Christian, Harter, Patrick N., Bähr, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783574/
https://www.ncbi.nlm.nih.gov/pubmed/29039591
http://dx.doi.org/10.3892/or.2017.6013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783574/
https://www.ncbi.nlm.nih.gov/pubmed/29039591
http://dx.doi.org/10.3892/or.2017.6013

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