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Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease
BRAF V600E mutations occur frequently in malignant melanoma, but are rare in most malignant glioma subtypes. Besides, more benign brain tumors such as ganglioglioma, dysembryoblastic neuroepithelial tumours and supratentorial pilocytic astrocytomas, only pleomorphic xanthoastrocytomas (50–78%) and e...
Autores principales: | Burger, Michael C., Ronellenfitsch, Michael W., Lorenz, Nadja I., Wagner, Marlies, Voss, Martin, Capper, David, Tzaridis, Theophilos, Herrlinger, Ulrich, Steinbach, Joachim P., Stoffels, Gabriele, Langen, Karl-Josef, Brandts, Christian, Senft, Christian, Harter, Patrick N., Bähr, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783574/ https://www.ncbi.nlm.nih.gov/pubmed/29039591 http://dx.doi.org/10.3892/or.2017.6013 |
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