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c-Fos mediates α1, 2-fucosyltransferase 1 and Lewis y expression in response to TGF-β1 in ovarian cancer

FUT1 is a key rate-limiting enzyme in the synthesis of Lewis y, a membrane-associated carbohydrate antigen. The aberrant upregulation of FUT1 and Lewis y antigen is related to proliferation, invasion and prognosis in malignant epithelial tumors. A c-Fos/activator protein-1 (AP-1) binding site was fo...

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Detalles Bibliográficos
Autores principales: Hao, Yingying, Zhu, Liancheng, Yan, Limei, Liu, Juanjuan, Liu, Dawo, Gao, Na, Tan, Mingzi, Gao, Song, Lin, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783580/
https://www.ncbi.nlm.nih.gov/pubmed/29130097
http://dx.doi.org/10.3892/or.2017.6052