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Downregulation of miR-874-3p promotes chemotherapeutic resistance in colorectal cancer via inactivation of the Hippo signaling pathway

Overcoming resistance to chemotherapy is an arduous challenge in the treatment of colorectal cancer (CRC), particularly since the underlying molecular mechanisms remain obscure. In the present study, we reported that miR-874-3p was markedly downregulated in CRC tissues compared with that in adjacent...

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Detalles Bibliográficos
Autores principales: Que, Kaiqian, Tong, Yuanhe, Que, Ganbo, Li, Li, Lin, Hongcheng, Huang, Shuai, Wang, Ruoyu, Tang, Langlang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783584/
https://www.ncbi.nlm.nih.gov/pubmed/29039607
http://dx.doi.org/10.3892/or.2017.6041