Antiproliferative effects of TSA, PXD-101 and MS-275 in A2780 and MCF7 cells: Acetylated histone H4 and acetylated tubulin as markers for HDACi potency and selectivity

Inhibition of histone deacetylase enzymes (HDACs) has been well documented as an attractive target for the development of chemotherapeutic drugs. The present study investigated the effects of two prototype hydroxamic acid HDAC inhibitors, namely Trichostatin A (TSA) and Belinostat (PXD-101) and the...

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Detalles Bibliográficos
Autores principales: Androutsopoulos, Vasilis P., Spandidos, Demetrios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783587/
https://www.ncbi.nlm.nih.gov/pubmed/29039546
http://dx.doi.org/10.3892/or.2017.6015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783587/
https://www.ncbi.nlm.nih.gov/pubmed/29039546
http://dx.doi.org/10.3892/or.2017.6015

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