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Downregulation of miR-19a-3p promotes invasion, migration and bone metastasis via activating TGF-β signaling in prostate cancer

Constitutive activation of TGF-β signaling pathway is a well-documented mechanism responsible for the bone metastasis of prostate cancer (PCa). MicroRNAs (miRNAs) have been reported to be crucial for the activation of TGF-β signaling via targeting downstream components of TGF-β signaling pathway. He...

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Detalles Bibliográficos
Autores principales: Wa, Qingde, Li, Li, Lin, Hongcheng, Peng, Xinsheng, Ren, Dong, Huang, Yan, He, Peiheng, Huang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783607/
https://www.ncbi.nlm.nih.gov/pubmed/29138858
http://dx.doi.org/10.3892/or.2017.6096