Anticancer pyridines induce G2/M arrest and apoptosis via p53 and JNK upregulation in liver and breast cancer cells

In the present study, the synthesis and biological evaluation of one novel pyridine and one novel pyridone anticancer compound is reported. The compounds 6-(2,4-dimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)-1H-pyridin-2-one (1) and 2-(2,4-dimethoxyphenyl)-4-(3,4-methylenedioxyphenyl)pyridine (2) wer...

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Detalles Bibliográficos
Autores principales: Androutsopoulos, Vasilis P., Spandidos, Demetrios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783619/
https://www.ncbi.nlm.nih.gov/pubmed/29207138
http://dx.doi.org/10.3892/or.2017.6116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783619/
https://www.ncbi.nlm.nih.gov/pubmed/29207138
http://dx.doi.org/10.3892/or.2017.6116

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