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Noise Induces Hopping between NF-κB Entrainment Modes

Oscillations and noise drive many processes in biology, but how both affect the activity of the transcription factor nuclear factor κB (NF-κB) is not understood. Here, we observe that when NF-κB oscillations are entrained by periodic tumor necrosis factor (TNF) inputs in experiments, NF-κB exhibits...

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Detalles Bibliográficos
Autores principales: Heltberg, Mathias, Kellogg, Ryan A., Krishna, Sandeep, Tay, Savaş, Jensen, Mogens H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783698/
https://www.ncbi.nlm.nih.gov/pubmed/28009264
http://dx.doi.org/10.1016/j.cels.2016.11.014