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A simple and rapid approach to develop recombinant avian herpesvirus vectored vaccines using CRISPR/Cas9 system

Herpesvirus of turkeys (HVT) has been successfully used as live vaccine against Marek's disease (MD) worldwide for more than 40 years either alone or in combination with other serotypes. HVT is also widely used as a vector platform for generation of recombinant vaccines against a number of avia...

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Detalles Bibliográficos
Autores principales: Tang, Na, Zhang, Yaoyao, Pedrera, Miriam, Chang, Pengxiang, Baigent, Susan, Moffat, Katy, Shen, Zhiqiang, Nair, Venugopal, Yao, Yongxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783714/
https://www.ncbi.nlm.nih.gov/pubmed/29269155
http://dx.doi.org/10.1016/j.vaccine.2017.12.025