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Aquaporin‐1 inhibition reduces metastatic formation in a mouse model of melanoma

Aquaporin‐1 (AQP1) is a proangiogenic water channel protein promoting endothelial cell migration. We previously reported that AQP1 silencing by RNA interference reduces angiogenesis‐dependent primary tumour growth in a mouse model of melanoma. In this study, we tested the hypothesis that AQP1 inhibi...

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Detalles Bibliográficos
Autores principales: Simone, Laura, Gargano, Concetta Domenica, Pisani, Francesco, Cibelli, Antonio, Mola, Maria Grazia, Frigeri, Antonio, Svelto, Maria, Nicchia, Grazia Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783831/
https://www.ncbi.nlm.nih.gov/pubmed/29044946
http://dx.doi.org/10.1111/jcmm.13378