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Aquaporin‐1 inhibition reduces metastatic formation in a mouse model of melanoma
Aquaporin‐1 (AQP1) is a proangiogenic water channel protein promoting endothelial cell migration. We previously reported that AQP1 silencing by RNA interference reduces angiogenesis‐dependent primary tumour growth in a mouse model of melanoma. In this study, we tested the hypothesis that AQP1 inhibi...
Autores principales: | Simone, Laura, Gargano, Concetta Domenica, Pisani, Francesco, Cibelli, Antonio, Mola, Maria Grazia, Frigeri, Antonio, Svelto, Maria, Nicchia, Grazia Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783831/ https://www.ncbi.nlm.nih.gov/pubmed/29044946 http://dx.doi.org/10.1111/jcmm.13378 |
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