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Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation

Bone destructive diseases are common worldwide and are caused by dysregulation of osteoclast formation and activation. During osteoclastogenesis, reactive oxygen species (ROS) play a role in the intracellular signalling triggered by receptor activator of nuclear factor‐κB ligand (RANKL) stimulation....

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yuuki, Kanzaki, Hiroyuki, Katsumata, Yuta, Itohiya, Kanako, Fukaya, Sari, Miyamoto, Yutaka, Narimiya, Tsuyoshi, Wada, Satoshi, Nakamura, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783833/
https://www.ncbi.nlm.nih.gov/pubmed/29063666
http://dx.doi.org/10.1111/jcmm.13367