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Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down‐regulation of phosphorylation of PPARγ in 3T3‐L1 cells

Accumulating evidence suggests that inhibition of mitogen‐activated protein kinase signalling can reduce phosphorylation of peroxisome proliferator‐activated receptor γ (PPARγ) at serine 273, which mitigates obesity‐associated insulin resistance and might be a promising treatment for type 2 diabetes...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Zhou, Min, Lang, Hedong, Zhou, Yong, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783835/
https://www.ncbi.nlm.nih.gov/pubmed/29160030
http://dx.doi.org/10.1111/jcmm.13403