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Gα12 regulates osteoclastogenesis by modulating NFATc1 expression

The G12 family of G protein alpha subunits has been shown to participate in the regulation of various physiological processes. However, the role of Gα12 in bone physiology has not been well described. Here, by micro‐CT analysis, we discovered that Gα12‐knockout mice have an osteopetrotic phenotype....

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Detalles Bibliográficos
Autores principales: Song, Min‐Kyoung, Park, Cheolkyu, Lee, Yong Deok, Kim, Haemin, Kim, Min Kyung, Kwon, Jun‐Oh, Koo, Ja Hyun, Joo, Min Sung, Kim, Sang Geon, Kim, Hong‐Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783869/
https://www.ncbi.nlm.nih.gov/pubmed/29077264
http://dx.doi.org/10.1111/jcmm.13370