CDK7 inhibition suppresses rheumatoid arthritis inflammation via blockage of NF‐κB activation and IL‐1β/IL‐6 secretion

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, joint tenderness and destruction of synovial joints, leading to severe disability. Anti‐inflammatory drugs and disease‐modifying anti‐rheumatic drugs (DMARDs) may improve RA process. However, in most patient...

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Detalles Bibliográficos
Autores principales: Hong, Honghai, Zeng, Yingmin, Jian, Wenxuan, Li, Lei, Lin, Liying, Mo, Yousheng, Liu, Meiling, Fang, Shuhuan, Xia, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783872/
https://www.ncbi.nlm.nih.gov/pubmed/29083085
http://dx.doi.org/10.1111/jcmm.13414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783872/
https://www.ncbi.nlm.nih.gov/pubmed/29083085
http://dx.doi.org/10.1111/jcmm.13414

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