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CDK7 inhibition suppresses rheumatoid arthritis inflammation via blockage of NF‐κB activation and IL‐1β/IL‐6 secretion
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint swelling, joint tenderness and destruction of synovial joints, leading to severe disability. Anti‐inflammatory drugs and disease‐modifying anti‐rheumatic drugs (DMARDs) may improve RA process. However, in most patient...
Autores principales: | Hong, Honghai, Zeng, Yingmin, Jian, Wenxuan, Li, Lei, Lin, Liying, Mo, Yousheng, Liu, Meiling, Fang, Shuhuan, Xia, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783872/ https://www.ncbi.nlm.nih.gov/pubmed/29083085 http://dx.doi.org/10.1111/jcmm.13414 |
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