Oxidative stress induces imbalance of adipogenic/osteoblastic lineage commitment in mesenchymal stem cells through decreasing SIRT1 functions

With rapidly ageing populations worldwide, the incidence of osteoporosis has reached epidemic proportions. Reactive oxygen species (ROS), a by‐product of oxidative stress and ageing, has been thought to induce osteoporosis by inhibiting osteogenic differentiation of mesenchymal stem cells (MSCs). Ho...

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Detalles Bibliográficos
Autores principales: Lin, Chia‐Hua, Li, Nan‐Ting, Cheng, Hui‐Shan, Yen, Men‐Luh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783884/
https://www.ncbi.nlm.nih.gov/pubmed/28975701
http://dx.doi.org/10.1111/jcmm.13356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783884/
https://www.ncbi.nlm.nih.gov/pubmed/28975701
http://dx.doi.org/10.1111/jcmm.13356

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