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Supramolecular aggregation of aquaporin‐4 is different in muscle and brain: correlation with tissue susceptibility in neuromyelitis optica

Neuromyelitis optica (NMO) is an autoimmune demyelinating disease of the central nervous system (CNS) caused by autoantibodies (NMO‐IgG) against the water channel aquaporin‐4 (AQP4). Though AQP4 is also expressed outside the CNS, for example in skeletal muscle, patients with NMO generally do not sho...

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Detalles Bibliográficos
Autores principales: Rosito, Stefania, Nicchia, Grazia Paola, Palazzo, Claudia, Lia, Anna, Buccoliero, Cinzia, Pisani, Francesco, Svelto, Maria, Trojano, Maria, Frigeri, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783885/
https://www.ncbi.nlm.nih.gov/pubmed/29055082
http://dx.doi.org/10.1111/jcmm.13401