Rescue of Outer Hair Cells with Antisense Oligonucleotides in Usher Mice Is Dependent on Age of Treatment

The absence of functional outer hair cells is a component of several forms of hereditary hearing impairment, including Usher syndrome, the most common cause of concurrent hearing and vision loss. Antisense oligonucleotide (ASO) treatment of mice with the human Usher mutation, Ush1c c.216G>A, corr...

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Detalles Bibliográficos
Autores principales: Ponnath, Abhilash, Depreux, Frederic F., Jodelka, Francine M., Rigo, Frank, Farris, Hamilton E., Hastings, Michelle L., Lentz, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783922/
https://www.ncbi.nlm.nih.gov/pubmed/29027038
http://dx.doi.org/10.1007/s10162-017-0640-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783922/
https://www.ncbi.nlm.nih.gov/pubmed/29027038
http://dx.doi.org/10.1007/s10162-017-0640-x

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