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Genomic profiling identifies GPC5 amplification in association with sarcomatous transformation in a subset of uterine carcinosarcomas

Uterine carcinosarcoma, also known as Malignant Mixed Müllerian Tumour, is a high‐grade biphasic neoplasm composed of sarcomatous elements thought to originate via transdifferentiation from high‐grade endometrial carcinoma. To identify molecular factors contributing to the histogenesis of this tumou...

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Detalles Bibliográficos
Autores principales: Chui, M Herman, Have, Cherry, Hoang, Lien N, Shaw, Patricia, Lee, Cheng‐Han, Clarke, Blaise A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783974/
https://www.ncbi.nlm.nih.gov/pubmed/29416878
http://dx.doi.org/10.1002/cjp2.89