Characterization of Dopaminergic System in the Striatum of Young Adult Park2(−/−) Knockout Rats

Mutations in parkin gene (Park2) are linked to early-onset autosomal recessive Parkinson’s disease (PD) and young-onset sporadic PD. Park2 knockout (PKO) rodents; however, do not display neurodegeneration of the nigrostriatal pathway, suggesting age-dependent compensatory changes. Our goal was to ex...

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Detalles Bibliográficos
Autores principales: Gemechu, Jickssa M., Sharma, Akhil, Yu, Dongyue, Xie, Yuran, Merkel, Olivia M., Moszczynska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784013/
https://www.ncbi.nlm.nih.gov/pubmed/29367643
http://dx.doi.org/10.1038/s41598-017-18526-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784013/
https://www.ncbi.nlm.nih.gov/pubmed/29367643
http://dx.doi.org/10.1038/s41598-017-18526-0

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