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Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer’s disease mouse model 5xFAD

Alzheimer’s disease (AD) is the most common form of dementia characterized by the formation of amyloid plaques (Aβ). Over the last decade, the important role of the innate immune system for the disease development has been established. Chronic activation of microglial cells creates a proinflammatory...

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Detalles Bibliográficos
Autores principales: Boza-Serrano, Antonio, Yang, Yiyi, Paulus, Agnes, Deierborg, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784016/
https://www.ncbi.nlm.nih.gov/pubmed/29367720
http://dx.doi.org/10.1038/s41598-018-19699-y