Embryonic Surface Ectoderm-specific Mitofusin 2 Conditional Knockout Induces Congenital Cataracts in Mice

Inherited mitochondrial mutations can result in mitochondrial dysfunction or stochastic oxidative damage. Cumulative mitochondrial damage is an important factor in age-related disorders, such as cataracts and macular degeneration. Mfn2 mediates the fusion of mitochondria and contribute to the dynami...

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Detalles Bibliográficos
Autores principales: Zhao, Jiangyue, Wu, Xinwei, Wu, Danhong, Yu, Yinhui, Yu, Yibo, Wang, Yao, Fu, Qiuli, Zhang, Jinsong, Yao, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784114/
https://www.ncbi.nlm.nih.gov/pubmed/29367651
http://dx.doi.org/10.1038/s41598-018-19849-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784114/
https://www.ncbi.nlm.nih.gov/pubmed/29367651
http://dx.doi.org/10.1038/s41598-018-19849-2

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