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Environmental pH modulates inerolysin activity via post-binding blockade

The cholesterol dependent cytolysins (CDCs) are a family of pore-forming toxins produced by a wide range of bacteria. Some CDCs are important virulence factors for their cognate organisms, but their activity must be tightly regulated to ensure they operate at appropriate times and within the appropr...

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Detalles Bibliográficos
Autores principales: Rampersaud, Ryan, Lewis, Emma L., LaRocca, Timothy J., Ratner, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784117/
https://www.ncbi.nlm.nih.gov/pubmed/29367601
http://dx.doi.org/10.1038/s41598-018-19994-8