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Proteomic Analysis of Nucleus Pulposus Cell-derived Extracellular Matrix Niche and Its Effect on Phenotypic Alteration of Dermal Fibroblasts

Reconstituting biomimetic matrix niche in vitro and culturing cells at the cell niche interface is necessary to understand the effect and function of the specific matrix niche. Here we attempted to reconstitute a biomimetic extracellular matrix (ECM) niche by culturing nucleus pulposus cells (NPCs)...

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Detalles Bibliográficos
Autores principales: Yuan, Minting, Pai, Pei-Jing, Liu, Xiaofen, Lam, Henry, Chan, Barbara P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784136/
https://www.ncbi.nlm.nih.gov/pubmed/29367647
http://dx.doi.org/10.1038/s41598-018-19931-9