Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition

Metabolic viability based high throughput assays like MTT and MTS are widely used in assessing the cell viability. However, alteration in both mitochondrial content and metabolism can influence the metabolic viability of cells and radiation is a potential mitochondrial biogenesis inducer. Therefore,...

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Detalles Bibliográficos
Autores principales: Rai, Yogesh, Pathak, Richa, Kumari, Neeraj, Sah, Dhananjay Kumar, Pandey, Sanjay, Kalra, Namita, Soni, Ravi, Dwarakanath, B. S., Bhatt, Anant Narayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784148/
https://www.ncbi.nlm.nih.gov/pubmed/29367754
http://dx.doi.org/10.1038/s41598-018-19930-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784148/
https://www.ncbi.nlm.nih.gov/pubmed/29367754
http://dx.doi.org/10.1038/s41598-018-19930-w

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