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Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens

The guanylate cyclase C (GC-C) receptor regulates electrolyte and water secretion into the gut following activation by the E. coli enterotoxin STa, or by weaker endogenous agonists guanylin and uroguanylin. Our previous work has demonstrated that GC-C plays an important role in controlling initial i...

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Detalles Bibliográficos
Autores principales: Amarachintha, Surya, Harmel-Laws, Eleana, Steinbrecher, Kris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784150/
https://www.ncbi.nlm.nih.gov/pubmed/29367634
http://dx.doi.org/10.1038/s41598-018-19868-z