Methylphenidate regulation of osteoclasts in a dose- and sex-dependent manner adversely affects skeletal mechanical integrity

Methylphenidate (MP) is the most prescribed psychostimulant for ADHD patients, with clinically demonstrated detrimental effects on bone quality, potentially leading to early onset osteoporosis and higher fracture risk. The underlying mechanism for the effects of MP on bone remains elusive. This stud...

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Detalles Bibliográficos
Autores principales: Uddin, Sardar M. Z., Robison, Lisa S., Fricke, Dennis, Chernoff, Evan, Hadjiargyrou, Michael, Thanos, Panayotis K., Komatsu, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784171/
https://www.ncbi.nlm.nih.gov/pubmed/29367750
http://dx.doi.org/10.1038/s41598-018-19894-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784171/
https://www.ncbi.nlm.nih.gov/pubmed/29367750
http://dx.doi.org/10.1038/s41598-018-19894-x

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