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Evaluation of Preexisting Anti-Hemagglutinin Stalk Antibody as a Correlate of Protection in a Healthy Volunteer Challenge with Influenza A/H1N1pdm Virus

Influenza virus hemagglutinin (HA) surface glycoprotein is currently the primary target of licensed influenza vaccines. Recently, broadly reactive antibodies that target the stalk region of the HA have become a major focus of current novel vaccine development. These antibodies have been observed in...

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Detalles Bibliográficos
Autores principales: Park, Jae-Keun, Han, Alison, Czajkowski, Lindsay, Reed, Susan, Athota, Rani, Bristol, Tyler, Rosas, Luz Angela, Cervantes-Medina, Adriana, Taubenberger, Jeffery K., Memoli, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784259/
https://www.ncbi.nlm.nih.gov/pubmed/29362240
http://dx.doi.org/10.1128/mBio.02284-17