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Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis
OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. Protein tyrosine phosphatase 1B (PTP1B), a negative modulator of insulin and cytokine signaling, is a therapeutic target for type 2 diabetes and obesity. We investigated the impact of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784331/ https://www.ncbi.nlm.nih.gov/pubmed/29126873 http://dx.doi.org/10.1016/j.molmet.2017.10.008 |