Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis

OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. Protein tyrosine phosphatase 1B (PTP1B), a negative modulator of insulin and cytokine signaling, is a therapeutic target for type 2 diabetes and obesity. We investigated the impact of...

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Detalles Bibliográficos
Autores principales: González-Rodríguez, Águeda, Valdecantos, M. Pilar, Rada, Patricia, Addante, Annalisa, Barahona, Inés, Rey, Esther, Pardo, Virginia, Ruiz, Laura, Laiglesia, Laura M., Moreno-Aliaga, María J., García-Monzón, Carmelo, Sánchez, Aránzazu, Valverde, Ángela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784331/
https://www.ncbi.nlm.nih.gov/pubmed/29126873
http://dx.doi.org/10.1016/j.molmet.2017.10.008

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