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The prospects of CRISPR-based genome engineering in the treatment of neurodegenerative disorders

Over the past few decades, as gene discovery methods and sequencing technologies have evolved, many genetic variations that significantly increase the risk of or cause neurodegenerative diseases have been identified. However, knowledge of those pathogenic mutations and subsequent mechanism-focused s...

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Detalles Bibliográficos
Autores principales: Shin, Jun Wan, Lee, Jong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784517/
https://www.ncbi.nlm.nih.gov/pubmed/29399048
http://dx.doi.org/10.1177/1756285617741837