Cargando…

Interferon gamma, an important marker of response to immune checkpoint blockade in non-small cell lung cancer and melanoma patients

BACKGROUND: Programmed death-ligand 1 (PD-L1) may be induced by oncogenic signals or can be upregulated via interferon gamma (IFN-γ). We have explored whether the expression of IFNG, the gene encoding IFN-γ, is associated with clinical response to the immune checkpoint blockade in non-small cell lun...

Descripción completa

Detalles Bibliográficos
Autores principales: Karachaliou, Niki, Gonzalez-Cao, Maria, Crespo, Guillermo, Drozdowskyj, Ana, Aldeguer, Erika, Gimenez-Capitan, Ana, Teixido, Cristina, Molina-Vila, Miguel Angel, Viteri, Santiago, De Los Llanos Gil, Maria, Algarra, Salvador Martin, Perez-Ruiz, Elisabeth, Marquez-Rodas, Ivan, Rodriguez-Abreu, Delvys, Blanco, Remedios, Puertolas, Teresa, Royo, Maria Angeles, Rosell, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784541/
https://www.ncbi.nlm.nih.gov/pubmed/29383037
http://dx.doi.org/10.1177/1758834017749748